DHPR的音标

Methods One hundred patients with unknown motor disturbance and mental retardation were referred to this study. All patients were performed by phenylalanine ( Phe) and BH4 loading test, urinary pterin analysis and dihydropteridine reductase ( DHPR) activity.

方法对100例运动及智能障碍患者进行苯丙氨酸（phenylalanine，Phe）及BH4负荷试验、尿蝶呤谱分析、红细胞二氢蝶啶还原酶测定，并对部分患者进行多巴治疗性诊断；

Urinary biopterin percentage and DHPR activity were all normal in 41 patients, so they were ruled out BH_ 4 deficiency.

41例尿蝶呤及DHPR活性均正常。

Conclusions The DHPR activity determination in red cell from dried blood spot is an effective, reliable and feasible method for diagnosis of DHPR deficiency.

结论干滤纸血片中红细胞DHPR活性测定是DHPR缺乏症有效、可靠且易行的诊断方法。